Comparing two inflammatory disease treatments for spine arthritis

This trial compares two types of biologic medications—IL-17 inhibitors and anti-TNF-alpha treatments—to see which one works better for ankylosing spondylitis (a chronic inflammatory disease of the spine). Both medications are already used to treat this condition, but this study wants to understand how they affect blood platelet counts and overall disease activity. The research may help doctors choose the best treatment option for future patients.

Currently, when standard pain medications don't work well enough, doctors turn to biologic treatments. However, not all patients respond equally to these medications, and some experience side effects. This study exists to understand whether one of these medications might be better at controlling inflammation while also managing blood cell counts, helping doctors make more personalized treatment decisions.