Plain-English translation of NCT06645691 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing a new way to take MRI images using hyperpolarized carbon-13 pyruvate, a specially prepared tracer that's injected into your bloodstream during the scan. The imaging technique helps doctors see how your heart and body's cells are using energy, which could help diagnose and monitor diseases like heart failure and metabolic conditions. Unlike older imaging methods, this approach doesn't expose you to radiation and can provide more detailed information about how your tissues are working.
Current imaging methods like PET scans can show how tissues use glucose, but they expose patients to radiation and don't reveal the full picture of how cells process energy. Researchers developed this new MRI-based approach to provide more detailed metabolic information without radiation exposure, which could help doctors diagnose diseases earlier and better track how well treatments are working.
You likely qualify if…
You likely don't qualify if…
You will come to the medical center for an MRI scan where a specially prepared tracer called hyperpolarized carbon-13 pyruvate will be injected into your vein while you're inside the MRI machine. The injection takes just a few seconds, followed by a saline flush, and then the MRI scanner will take images to capture how your heart and body tissues are using energy. The entire procedure is done in one visit and doesn't involve exposure to radiation.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
Singapore