Plain-English translation of NCT06652763 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are using a new type of heart MRI scan with a special dye called manganese to take detailed pictures of how hearts work in people with heart failure and preserved ejection fraction (a condition where the heart can't fill with blood properly). The study will compare hearts of people with this condition who have type 2 diabetes, those without diabetes, and healthy volunteers to understand why diabetes makes heart failure worse.
Heart failure with preserved ejection fraction is very common but doctors don't yet understand why it develops or how to treat it effectively. When diabetes and this type of heart failure occur together, patients have worse outcomes. This study exists to uncover what's different about how diabetic hearts handle calcium and energy, which are critical for the heart to pump and fill properly.
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If you enroll, you will come in for a specialized heart MRI scan that uses manganese contrast dye to create detailed images of your heart's structure, function, calcium handling, and energy use. The scan itself typically takes 30–60 minutes, and you may have some blood work or other routine heart assessments before or after. Most participants complete the study in one or two visits, though you should ask your research team for specific details about timing and any follow-up appointments.
AI-generated summary from trial data · Aug 9, 2026 · Not medical advice
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