Plain-English translation of NCT06654401 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atrial Fibrillation research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Atrial fibrillation is an irregular heartbeat that can be treated with a procedure called catheter ablation, which uses radiofrequency energy to fix the problem areas in your heart. This trial is comparing two approaches: some patients will receive electrical cardioversion (a controlled electrical shock to restore normal heartbeat) before their ablation procedure, while others will go directly to ablation. The study wants to see if the electrical shock beforehand helps people maintain a normal, steady heartbeat after the ablation.
When atrial fibrillation has persisted for a long time, the heart muscle can become damaged and scarred, making it harder for ablation alone to work. Researchers want to know whether using electrical cardioversion first can help reverse some of this damage and improve the chance that your heart stays in normal rhythm after the ablation procedure.
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If you join this study, you will be randomly assigned to receive either electrical cardioversion before your ablation procedure or to go directly to ablation without it. Either way, you will undergo the radiofrequency catheter ablation to treat your atrial fibrillation. After your procedure, you will return for follow-up visits at 3 months, 6 months, and 12 months, where you will have heart ultrasounds, standard heart rhythm tests (ECG), and 24-hour heart rhythm monitoring to see how well your treatment worked.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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