Plain-English translation of NCT06657222 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is one of the first times this treatment has been tested in people.
This is a first-in-human study testing a new cancer drug called to see if it can help treat advanced solid tumors in adults. The trial will first find the safest and most effective dose, then test the medication in two specific cancer types: head and neck cancer and non-small cell lung cancer. Researchers want to understand both how safe this treatment is and whether it actually works against cancer.
Many people with advanced solid tumors have limited treatment options, and current therapies don't work for everyone. This medication is designed to target cancer cells in a new way, so researchers are testing it to see if it could offer patients another option.
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You would receive the medication through an IV infusion every three weeks and visit the clinic every three weeks for checkups, blood tests, and imaging scans to monitor how you're responding. During the trial, you'll also answer questionnaires about any side effects or symptoms you experience. The study starts with a dose-escalation phase to find the safest dose, then moves to a phase that tests two specific doses in patients with head and neck cancer or lung cancer to determine which dose works best.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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