Plain-English translation of NCT06657404 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
If you've had a catheter ablation procedure for atrial fibrillation (an irregular heart rhythm) and your irregular heartbeats have come back, this trial is testing whether taking amiodarone combined with two other medications works better than taking just two of those medications. Researchers want to see if this three-drug approach can help keep your heart rhythm stable after your procedure.
Some patients continue to have irregular heartbeats even after catheter ablation, and doctors need better ways to prevent these episodes from returning. This trial is testing whether this three-drug combination is more effective at restoring and maintaining a normal heart rhythm than current standard treatment.
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If you are selected for this trial, you will be randomly assigned to either take the three-medication combination or a two-medication combination. You will take your assigned medications regularly and attend follow-up visits so doctors can monitor whether your heart rhythm stays stable and whether the treatment is working well for you. The trial involves 328 patients across multiple hospitals who will be tracked to compare how well each treatment approach prevents irregular heartbeats from returning.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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