Plain-English translation of NCT06661876 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new approach called external beam radiotherapy (EBRT) — a single, targeted radiation treatment delivered to the whole heart — for patients with advanced heart failure that hasn't responded well to standard medications. Researchers believe this treatment might improve how well the heart pumps blood by about 5%, which could make a meaningful difference in how you feel. The study will enroll 40 patients to see if this treatment is safe and effective.
Heart failure is serious and some patients continue to struggle even after taking all recommended medications. This trial exists because early evidence suggests that a carefully controlled radiation treatment might help the heart function better in these hard-to-treat cases, offering hope to patients who have limited options.
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If you join this trial, you would receive a single radiation treatment session that targets your whole heart — similar to radiation therapy used for other conditions, but a low, controlled dose. You would need to return for follow-up visits and tests to help doctors monitor how well the treatment is working, how you feel, and whether you experience any side effects. The study will track your heart function, hospital visits, quality of life, and blood tests over time to understand the full impact of the treatment.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
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