Testing a new spinal injection treatment for early-stage ALS

This study is testing a new investigational medication called AMX0114 to see if it is safe and can be tolerated by people with ALS. The medication is given as an injection into the spinal fluid in the lower back—a procedure similar to a lumbar puncture. Researchers will carefully monitor how your body responds to the treatment and whether it affects the biological markers associated with ALS progression.

ALS is a serious condition that causes nerve cells to die, leading to muscle weakness and loss of function. This trial exists to determine whether this new treatment approach is safe enough to potentially help people in the early stages of the disease and to gather information about how it works in the body.