Testing a new stent graft device for liver cirrhosis complications

Plain-English translation of NCT06669806 on ClinicalTrials.gov ↗ · Source last updated December 2025 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing the LIVERTYTM TIPS Stent Graft, a small device placed inside your liver to help improve blood flow and reduce dangerous complications from cirrhosis. The device works by creating a channel between two blood vessels in your liver, which can help prevent life-threatening bleeding and reduce fluid buildup in your belly. Researchers will follow you for 12 months to see how well the device works and whether it stays open over time.

People with advanced liver cirrhosis often develop serious complications like variceal bleeding (dangerous bleeding from enlarged veins), ascites (fluid buildup in the belly), and other problems related to high blood pressure in the liver. This trial is testing a new treatment option to help manage these complications and improve quality of life.

Do you qualify?

You likely qualify if…

you are between 18 and 75 years old
you have been diagnosed with liver cirrhosis and portal hypertension (high blood pressure in the liver)
you have experienced variceal bleeding, fluid buildup in your belly, or other complications from cirrhosis
you have adequate liver function (based on MELD and Child-Pugh scores) and a platelet count above 20×10^9/L
you can understand the trial, agree to participate, and commit to 12 months of follow-up visits

You likely don't qualify if…

you are pregnant, breastfeeding, or planning to become pregnant during the trial
you have had a previous TIPS procedure, surgical shunt, or certain other liver interventions (unless you had retrograde transvenous obliteration at least 8 weeks before)
you have severe liver disease with certain complications, such as grade 2 or higher hepatic encephalopathy, severe blood clotting problems, or very high bilirubin levels
you have a blood clot in your main portal vein, heart failure, recent heart attack (within 3 months), or uncontrolled infection
you are allergic to contrast dye or any materials in the stent graft device

What participation looks like

If you qualify, you will receive the LIVERTYTM TIPS Stent Graft device during a procedure where doctors create a channel between two blood vessels in your liver and place the device to keep that channel open. You will then be followed for 12 months with regular visits and imaging to check that the device is working properly and monitor your health. The study will track your symptoms, any complications, and how well the device prevents future bleeding or other problems.

AI-generated summary from trial data · Jun 19, 2026 · Not medical advice

Trial locations(1 site)

China

Hunan Provincial People's Hospital, Changsha, Hunan