Plain-English translation of NCT06670781 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a guided breathing technique using a pressure device can better detect a patent foramen ovale (a small opening between two chambers of the heart) compared to the standard self-directed breathing method. Patients who have had a stroke without a clear cause may have this heart opening, which can sometimes be closed to prevent another stroke. The study wants to see if the guided method finds more cases.
About one-third of strokes happen without doctors finding an obvious cause, and a small heart opening may be responsible. The current breathing technique doctors use relies on patients following general instructions, which can be inconsistent. This trial is testing whether a more controlled, guided breathing method would be more reliable and catch more cases of this heart condition.
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You will come in for a heart ultrasound and complete two different breathing techniques while the doctor performs the ultrasound. First, you will use the standard method where you're instructed to bear down or strain. Then, you will use a guided method where you blow into a tube connected to a pressure device until you reach a specific pressure level. The whole process takes place during your regular ultrasound appointment, and both techniques happen on the same day.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
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