Plain-English translation of NCT06675422 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This is an early-stage clinical trial testing JY231, an experimental injectable medication for people with active systemic lupus erythematosus (SLE) that hasn't been adequately controlled by standard treatments. The study will enroll approximately 10–20 patients to evaluate whether this medication is safe and whether it helps reduce lupus activity. Researchers will carefully monitor you for side effects and measure how well the treatment works.
Lupus is a serious autoimmune disease where the body attacks its own tissues, causing inflammation and damage. While current treatments help many people, some patients—like those in this trial—continue to experience active disease despite being on multiple medications. This trial is testing whether the new treatment could be a helpful option for people whose lupus remains uncontrolled.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will receive JY231 injections as part of your treatment, with visits to the study center where researchers will monitor you closely for any side effects and evaluate how well the medication is controlling your lupus. The study will measure your response through blood tests, disease activity assessments, and clinical evaluations. Since this is an early-stage trial with a small number of participants, close follow-up and safety monitoring will be emphasized throughout your involvement.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China
Phase
Safety & dosing / Early efficacy
Sponsor
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
Enrollment target
~20 participants
Started
October 2024
Primary completion
September 2026
Age range
14 Years – 75 Years
Last updated on clinicaltrials.gov in November 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Sanbin Wang, Doctor
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.