Plain-English translation of NCT06677944 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a new approach to treating early-stage breast cancer called preoperative partial breast irradiation (PBI). Instead of having radiation therapy after surgery, you would receive it before surgery. Researchers want to see if this order of treatment works just as well and causes fewer side effects than the traditional approach.
Currently, most breast cancer patients receive radiation after surgery. This trial exists to find out whether doing radiation first might reduce pain, scarring, and other side effects while keeping the same cancer-fighting benefits.
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You would receive radiation therapy to the breast over several weeks, then have breast cancer surgery 2–3 months later. You would visit the clinic multiple times for radiation treatments, and then return for follow-up visits at 6 months and 12 months after radiation to check for side effects, healing, breast appearance, and how well the treatment worked. Throughout the study, you would complete questionnaires about your quality of life and undergo imaging scans and special measurements of your breast.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
South Korea