Plain-English translation of NCT06678880 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Depression research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study investigates whether depression and sleep problems during menopause are caused by disrupted internal body rhythms, and whether correcting those rhythms through timed sleep restriction and bright light therapy can help. Researchers believe hormonal changes during menopause can throw off your body's natural clock, which affects mood and sleep. The trial will test whether one night of early sleep followed by two weeks of morning bright light exposure can reset your body clock and improve your mood and sleep quality.
Many women experience depression and poor sleep during menopause, but current treatments don't work for everyone. This trial exists to test a new approach based on the idea that menopausal depression may be rooted in a disrupted internal body clock—and that fixing the timing of your sleep and light exposure might help without needing additional medications.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will be randomly assigned to one of two groups. Both groups will have one night of restricted sleep followed by two weeks of 30-minute daily bright light exposure—but the timing will differ between groups. One group will sleep earlier in the night and get bright light in the morning, while the other group will sleep later and get bright light in the evening. Researchers will measure your mood, sleep quality, and internal body clock markers (like melatonin levels) throughout the study to see which approach works better.
AI-generated summary from trial data · Jun 20, 2026 · Not medical advice
United States