Plain-English translation of NCT06679543 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers have noticed that men and women respond differently to exercise after not getting enough sleep. This trial is investigating how sleep deprivation affects the heart's pumping ability (called cardiac output) during cycling in both men and women. By measuring blood pressure, heart function, and other markers before, during, and after exercise, the study aims to understand why these sex differences exist.
Previous research showed that men's blood pressure behaves differently during exercise after a poor night's sleep compared to women, even when they're working equally hard. This trial exists to uncover the underlying reason—specifically, whether the heart pumps less efficiently in men after sleep loss. Understanding this difference could lead to better guidance for people about exercise safety when they haven't slept well.
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You'll make three visits to the lab. On your first visit, researchers will measure your fitness level during a maximum exercise test. On the next two visits (in random order), you'll arrive after either a normal night of sleep or a night where you wake up much earlier than usual (getting only about 40% of your usual sleep). Each of these testing days involves cycling for 60 minutes at a steady pace while researchers measure your heart function, blood pressure, and other responses using ultrasound and blood draws before, during, and after exercise.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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