Plain-English translation of NCT06680791 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is looking at the genetic mutations (changes in DNA) found in endometrial cancer tumors to better understand which patients are at higher risk of cancer coming back. Researchers will examine tissue samples and blood to identify specific genetic patterns and see how they connect to lifestyle factors like weight, blood pressure, and diabetes.
Endometrial cancer patients have different genetic profiles that may predict how likely their cancer is to return, but doctors don't yet have a clear way to identify high-risk patients or monitor them for recurrence. This study aims to discover genetic signatures in blood that could help catch cancer early if it comes back and guide treatment decisions.
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As a participant, you would provide samples of your cancer tissue (already removed during surgery) and blood samples so researchers can examine your genetic mutations. You may also be asked to share information about your lifestyle, weight, medical history, and other health factors to help researchers understand how these connect to your cancer's genetics. The study involves no additional surgery or medication.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Czechia
National Institute of Public Health, Czech Republic
Enrollment target
~280 participants
Started
July 2024
Primary completion
December 2027
Sex
Female only
Last updated on clinicaltrials.gov in November 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Michael Halaška, prof. MUDr.
Medical director
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.