Plain-English translation of NCT06681896 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new approach called MICROFIT to help people with microvascular coronary dysfunction — a condition where the tiny blood vessels in your heart don't work as well as they should, causing chest pain. The MICROFIT program combines personalized one-on-one exercise training (including high-intensity interval training) and dietary guidance based on a Mediterranean-style diet, delivered over 24 weeks. Researchers want to see if this intensive, personalized approach works better than standard care alone.
Many people with microvascular coronary dysfunction suffer from ongoing chest pain that isn't fully controlled by medications. Currently, these patients receive only general lifestyle advice. This trial exists to test whether a more intensive, personalized exercise and diet program can better relieve symptoms and improve quality of life.
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If you join this study, you will be randomly assigned to either receive the MICROFIT program or standard care. If you receive MICROFIT, you'll work with a personal trainer for 24 weeks on a customized exercise program (including high-intensity interval training) and receive dietary guidance focused on Mediterranean-style eating. You'll have one-on-one sessions and home-based exercise support throughout. Both groups will have regular check-ins with a cardiologist. The study will track your chest pain symptoms and other health measures to see if the personalized program helps you feel better.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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