Comparing lung function and physical health in three groups

Plain-English translation of NCT06682832 on ClinicalTrials.gov ↗ · Source last updated March 2026 · Translation generated June 2026 · How we translate trials

What is this trial?

This research study is comparing three groups of adults over age 40: those with COPD (a chronic lung disease), those with a related condition called PRISM (preserved ratio impaired spirometry), and healthy adults. Researchers want to understand how PRISM affects the body — including lung function, muscle strength, exercise ability, blood vessel stiffness, and quality of life — to see if it causes similar problems to COPD.

PRISM is a lung condition that is common but not well understood. Some people have symptoms and problems with exercise and daily life, but doctors don't know exactly how serious it is or how it compares to COPD. This study aims to fill that gap by measuring how PRISM affects the body in multiple ways.

Do you qualify?

You likely qualify if…

you are over 40 years old
you have been diagnosed with PRISM, COPD, or are in good health with no chronic conditions
your condition is stable and you are not experiencing a flare-up or exacerbation
you are willing to volunteer and can cooperate with physical measurements and tests
you do not have severe bone, nerve, or heart problems that would prevent you from participating

You likely don't qualify if…

you have severe problems with your bones, nerves, or heart
you are currently experiencing a COPD flare-up or exacerbation
you have other chronic health conditions (for the healthy control group)
you are unable or unwilling to cooperate with the study measurements and tests

What participation looks like

You would visit the research center for testing sessions where doctors and researchers will measure your lung function using breathing tests, test your muscle strength, have you perform an exercise test to see how far you can walk or exercise, and take measurements of your blood vessel stiffness and muscle oxygenation. You may also complete surveys about your physical activity, sleep, and quality of life. The study involves no medication — only measurements and tests to compare your physical and lung health with the other groups.

AI-generated summary from trial data · Jun 5, 2026 · Not medical advice

Trial locations(1 site)

Turkey (Türkiye)

Hacettepe University, Ankara