Plain-English translation of NCT06685965 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called (dexmedetomidine) to see if it can help people with PTSD who struggle with sleep problems. You would spend several nights in a sleep laboratory where researchers monitor your sleep while you receive either a low dose, a high dose, or a placebo (inactive pill). The study is designed to find the best dose and confirm that the medication is safe.
Many people with PTSD have serious sleep problems that don't respond well to current treatments. Researchers want to see if this medication could offer a new option to help them sleep better and improve their quality of life.
You likely qualify if…
You likely don't qualify if…
You would come to the sleep laboratory for one screening night, followed by three treatment nights. During each treatment night, you receive either a low dose of the medication, a high dose, or a placebo—but neither you nor the research team will know which one you're getting. Researchers will monitor your sleep using standard equipment (like electrodes on your head) throughout your stays. The study takes about a week total.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Switzerland