Plain-English translation of NCT06686537 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research study is testing how an estradiol patch — a small patch that delivers the hormone estrogen through your skin — affects your body's natural hormone surges. The researchers want to understand whether estradiol works the same way in women of different body weights. By comparing two groups of women, they hope to learn more about hormonal patterns related to fertility and metabolism.
Some women struggle with fertility or hormonal imbalances, and researchers believe that weight may play a role in how reproductive hormones work. This study aims to understand the biological reasons behind these differences so doctors can eventually develop better treatments.
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You would visit the clinic for a screening appointment lasting up to 3 weeks, where your basic health will be checked. Then during the treatment period (7–10 days), you would wear a small estradiol patch for 7 days, have one blood draw on day 3, and collect your first morning urine every day you're wearing the patch. The entire study takes about 2–3 weeks total.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States