Plain-English translation of NCT06686537 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research study is testing how —a form of the hormone estrogen delivered through your skin—affect your body's hormonal signals in two groups of women: those with normal weight and those with higher weight. The researchers want to understand if the medication works differently depending on body weight, which could help explain why some women have fertility challenges.
Many women struggle with infertility and irregular hormones, and the reasons are not fully understood, especially how body weight affects these hormonal patterns. This study aims to uncover the basic mechanisms behind these issues so doctors can better help women in the future.
You likely qualify if…
You likely don't qualify if…
You will attend a screening visit lasting up to 3 weeks, followed by a treatment period of 7–10 days. During treatment, you'll wear an estradiol patch on your skin for 7 days, have one blood draw on day 3, and collect your first morning urine sample every day while wearing the patch. The entire study commitment is relatively short, and all visits take place at one location.
AI-generated summary from trial data · Aug 3, 2026 · Not medical advice
United States