Plain-English translation of NCT06687122 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand whether adding eggs to your daily diet can help improve how your body processes fats and sugars, particularly in your liver. This is a Phase I study that will enroll 20 adults with obesity to see if eating three whole eggs per day for four weeks affects liver function, cholesterol levels, blood sugar, and other metabolic markers. The study focuses on a nutrient in eggs called choline, which plays an important role in liver health.
People with obesity often develop fatty liver disease, which can harm their health. Early research suggests that choline — a nutrient found in eggs — may help the liver work better and manage fat more effectively. However, scientists don't yet know whether eating eggs as a whole food can improve liver health in people with obesity, or whether the benefit varies from person to person based on genetics and gut bacteria.
You likely qualify if…
You likely don't qualify if…
You would participate in a 12-week study with three phases. First, you'll spend four weeks eating your normal diet while researchers collect baseline information. Next, you'll spend four weeks adding three whole eggs to your daily diet while researchers monitor changes in your liver, cholesterol, blood sugar, and other health markers. Finally, you'll have a four-week washout period where you return to your normal diet without eggs. Throughout the study, you'll likely have blood tests and possibly imaging (like scans) to measure liver health and metabolism.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Canada
Sponsor
University of Guelph
Collaborators
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Enrollment target
~20 participants
Started
January 2025
Primary completion
December 2026
Age range
30 Years – 65 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Clara E. Cho, PhD
University of Guelph
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.