Plain-English translation of NCT06690528 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether surgery to remove pancreatic cancer and spots in the liver works better than continuing chemotherapy alone for patients whose cancer has responded well to initial treatment. Researchers believe that completely removing the primary tumor and liver metastases may help control the disease better and improve survival. The trial will compare these two approaches in about 56 patients across multiple hospitals.
Pancreatic cancer that has spread to the liver is usually treated with chemotherapy, but doctors are now investigating whether aggressive surgery—after chemotherapy has worked—might help patients live longer and control their disease better. This trial exists to answer an important question: for patients whose cancer is stable or shrinking, is surgery the right next step?
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If you join this trial, you will be randomly assigned to one of two groups: the surgery group, where you will have an operation to remove your pancreatic tumor and liver spots (followed by possible additional chemotherapy or radiation), or the observation group, where you will continue chemotherapy or be observed without surgery. You will have regular follow-up visits and imaging tests to monitor how well the treatment is working and to track your health over time.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
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