Comparing two blood-thinning medications after heart stent placement

This trial is testing whether people who have received a heart stent can safely stop taking two blood-thinning medications together and switch to just one. The study will compare two different single medications—prasugrel and ticagrelor—to see which one works better and causes fewer side effects when used alone after the first few months following stent placement.

After a heart stent, patients typically take two blood-thinning medications together for about a year to prevent clots. However, this combination increases the risk of serious bleeding. Recent research suggests that switching to a single, more potent blood-thinner after a few months might reduce bleeding without raising the risk of heart problems—but doctors need to know which single medication is safest and most effective.