Plain-English translation of NCT06692751 on ClinicalTrials.gov ↗ ·
Microvascular angina affects millions of people worldwide but is hard to diagnose because the problem involves tiny blood vessels in the heart that don't show up on standard heart imaging. Currently, doctors use an invasive test called the microcirculatory resistance index to confirm this condition. This study is testing whether a simple, quick, non-invasive eye scan — called optical coherence tomography angiography — can detect the same tiny blood vessel problems, potentially offering patients an easier way to get diagnosed.
Right now, the only reliable way to confirm microvascular angina requires an invasive procedure during heart catheterization. If doctors can show that an eye scan reveals the same information as this invasive test, patients could be diagnosed with a simple, painless office visit instead — saving time, money, and discomfort.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be placed into one of two groups based on your microcirculatory resistance index results from your recent heart test. You will then undergo a simple eye scan called OCT-A to measure blood vessel density in your retina — a quick, painless procedure done in an office setting. The study will follow you for 12 months to compare whether the eye scan results match your heart test results, potentially validating eye imaging as a non-invasive alternative for diagnosing microvascular angina.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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