Plain-English translation of NCT06697938 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether combining radiation therapy with chemotherapy before surgery works better than chemotherapy alone for people with advanced breast cancer. The study wants to see if adding radiation helps shrink tumors more effectively, makes it possible to save more of the breast, and reduces side effects using modern radiation techniques.
Many patients with advanced breast cancer still have poor outcomes even with current treatments. This trial exists to find out whether the new treatment approach can help more patients avoid mastectomy, achieve better tumor response, and have fewer complications compared to chemotherapy alone.
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If you join this trial, you will be randomly assigned to receive either chemotherapy alone or chemotherapy combined with radiation therapy before your breast cancer surgery. You will have regular visits for treatment, imaging scans to monitor your progress, and blood tests. After completing the preoperative treatment, you will have surgery, and the research team will follow you to track how well the treatment worked and monitor for any side effects.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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