Plain-English translation of NCT06698666 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Major Depressive Disorder research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
Researchers want to know if rosuvastatin—a medication normally used to manage cholesterol—might also help reduce depression symptoms when combined with standard depression treatment. You would take either your regular depression medication alone, or your regular depression medication plus rosuvastatin. The study will compare how well each approach works.
Many people with depression don't feel better with standard medications alone. Scientists have noticed that this medication might have additional benefits for mood, so they want to test whether adding it to regular depression treatment could help more patients recover.
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You will visit the psychiatry clinic at El Demerdash Hospital and be randomly assigned to either take your regular depression medication alone, or to add a daily 10 mg dose of rosuvastatin to your treatment. Throughout the study, clinic staff will monitor how you're feeling using depression rating scales and watch for any side effects. The study continues until enough participants are enrolled to give researchers a clear answer.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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