Plain-English translation of NCT06699602 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether two immunotherapy medications called and can be safely given before surgery to remove a kidney affected by cancer. Researchers want to see if this treatment shrinks the tumor, whether it's safe, and whether it delays your planned surgery. All participants will receive the same treatment: three doses of these medications given three weeks apart.
Right now, people with advanced kidney cancer typically have surgery first, then receive immunotherapy afterward. This study is exploring whether giving this treatment before surgery might work better by shrinking the tumor first and potentially improving outcomes.
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You would receive the two immunotherapy medications by infusion every three weeks for a total of three treatments, unless side effects become too severe. During this time, doctors will monitor you closely with blood tests and imaging to see how your tumor responds. After completing the three doses, you will have your planned kidney surgery. The entire pre-surgery treatment phase lasts about 9 weeks.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
United States