Plain-English translation of NCT06705036 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying invasive pituitary tumors — tumors that have already spread into surrounding areas — to understand what makes them aggressive. The study collects paired tumor tissue samples from two different regions of the tumor (the central area and an area that has spread into nearby structures) and analyzes their molecular makeup using advanced laboratory techniques. The goal is to discover why tumors behave differently in different regions and to find new ways to treat them.
Some pituitary tumors spread aggressively while others remain contained, but doctors don't fully understand why. By comparing the molecular characteristics of the same tumor in different locations, researchers hope to uncover the biological drivers of aggressive growth and identify new targets for future treatments.
You likely qualify if…
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If you qualify and choose to participate, your involvement is primarily based on your scheduled surgery to remove the tumor. During that surgery, researchers will collect small paired tissue samples from two regions of your tumor — your surgeon will do this as part of your standard treatment. These samples will be frozen and analyzed using molecular techniques like gene and protein analysis. You may also have your existing imaging scans (MRI or CT) reviewed as part of the study. There are no additional visits or treatments required beyond your normal surgical care.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
China
Sponsor
Shanghai Zhongshan Hospital
Enrollment target
~20 participants
Started
November 2024
Primary completion
November 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in November 2024.
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Central contact
Tao Xie
Fudan University
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