Understanding Heart Disease Risk in Men with Haemophilia

The CACHE Study is looking at heart and blood vessel health in men with haemophilia. As people with haemophilia live longer thanks to better treatments, doctors are noticing that some develop heart disease. This study uses special imaging scans to understand how blood vessel damage develops in haemophilia and whether it happens differently than in people without the condition.

Historically, people with haemophilia have had lower rates of heart disease than the general population, but doctors don't fully understand why. This research will help answer whether this is because blood vessels develop damage more slowly, or because the clotting factor deficiency actually protects against dangerous blood clots. Understanding this is important for keeping aging men with haemophilia healthy.