Plain-English translation of NCT06706323 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
After heart bypass surgery, about 30% of patients develop significant depression — four times higher than in the general population. This study is building a prediction tool that will help doctors identify which patients are most at risk for depression before or right after surgery, so they can step in with support early on. Researchers will collect information about your health, mood, blood markers, and how your heart responds to stress.
Depression after heart surgery is serious—it leads to worse quality of life and can even increase the risk of death. Right now, doctors don't have a reliable way to predict which patients will struggle with depression, so many people don't get help until it's already a problem. This study aims to change that by creating a tool that catches at-risk patients early.
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You will be asked to complete surveys and provide information about your mental health, mood, and medical history before your surgery. Researchers will also collect blood samples to measure inflammation markers and test how your body responds to stress. After surgery, you'll complete follow-up assessments at 6 weeks to see how you're doing emotionally. The study uses two hospitals—you'll be in either the training group (which helps build the prediction tool) or the testing group (which validates it works).
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
Switzerland