Plain-English translation of NCT06706544 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether can help ease numbness and tingling that develops after chemotherapy treatment. The study will compare patients who receive alongside their regular care to those who receive a placebo (inactive oxygen only). Researchers want to see if this medication reduces nerve-related symptoms and improves how patients feel day-to-day.
Numbness and tingling from chemotherapy can be severe enough to force patients to stop or reduce their cancer treatment, which limits how well that treatment works. Currently, there are very few options available to help these symptoms, so doctors are exploring whether this medication might offer relief.
You likely qualify if…
You likely don't qualify if…
You will receive either ozone or placebo therapy through rectal insufflation (a gentle procedure where gas is introduced into the rectum) as an add-on to your regular medical care. You will attend 40 treatment sessions over 16 weeks, roughly twice a week. Throughout the study, you will complete questionnaires about your symptoms, nerve sensations, mood, and quality of life, and may have some blood tests and special imaging scans of your hands and feet. The study will follow you for about 28 weeks total.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
Spain