Plain-English translation of NCT06709196 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
After bladder removal surgery (cystectomy), many patients develop infections that send them back to the hospital. This trial is testing a new approach: instead of giving everyone the same antibiotic called , doctors will test your urine first to see what bacteria you have, then give you an antibiotic that targets your specific bacteria. The hope is this personalized approach will prevent more infections than the standard one-size-fits-all method.
Right now, about 1 in 3 patients who have their bladder removed end up back in the hospital with an infection within 90 days. Doctors don't have clear evidence about which antibiotics work best or when to give them, so different hospitals use different approaches. This medication aims to be smarter and more targeted, which could reduce unnecessary infections and help use antibiotics more wisely.
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Before surgery, you'll have a urine test and fill out two quality-of-life questionnaires. After your bladder removal surgery, when your ureteral stent (a small tube) is removed, you'll randomly receive one of two antibiotic treatments: either the standard three doses of one antibiotic spread throughout the day, or a single-day course of an antibiotic chosen specifically for any bacteria found in your urine sample. The trial follows you for 90 days after surgery to track whether you develop any infections that require readmission to the hospital.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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