Plain-English translation of NCT06715514 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial investigates whether combining (estrogen and progesterone patches) with semaglutide — a medication used to help control blood sugar and weight — works better together than the diabetes medication alone. The study focuses on women who have recently entered menopause and are dealing with diabetes or prediabetes. Researchers believe that restoring estrogen levels during menopause may enhance how well the medication works.
After menopause, dropping estrogen levels make it harder for women to control their blood sugar and weight, and increase the risk of developing or worsening diabetes. While both hormone therapy and the medication have shown benefits separately, doctors don't yet know whether using them together could provide even better results.
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You would be randomly assigned to receive either the diabetes medication alone, or both the hormone therapy patch (worn on your skin) plus the diabetes medication. The medication involves a weekly injection that starts at a low dose and gradually increases over 8 weeks. You would also receive a hormone patch to wear and possibly a progesterone pill if you still have a uterus. Throughout the study, you would attend clinic visits to have blood tests, weight checks, and assessments of your symptoms and how you are managing.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Switzerland