Plain-English translation of NCT06720246 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how two obesity treatments—bariatric surgery and a medication called liraglutide—change how your brain works. Specifically, they're looking at whether these treatments help your brain become less drawn to high-calorie foods and better at resisting cravings. This study will help doctors understand why some weight-loss treatments work better than others for long-term success.
We know that obesity involves changes in how the brain responds to food, making it harder to feel full and easier to crave unhealthy foods. While surgery and this medication both help people lose weight, scientists don't yet know exactly how they change these brain processes, which could help improve treatments in the future.
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If you join this study, you will either undergo bariatric surgery, receive liraglutide treatment, or follow a dietary program—whichever you and your doctor have already planned. Alongside your treatment, researchers will use brain imaging scans and cognitive tests to measure how your brain's response to food changes over time. The study will involve multiple clinic visits to assess your progress and perform these specialized tests.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
Italy
Sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Enrollment target
~50 participants
Started
June 2024
Primary completion
May 2027
Age range
20 Years – 60 Years
Last updated on clinicaltrials.gov in December 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Eraldo Paulesu, MD
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.