Plain-English translation of NCT06720922 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a newer, less invasive laser surgery (called MRgLITT) works as well as traditional open brain surgery for treating mesial temporal lobe epilepsy—a form of epilepsy that doesn't respond well to medications. The laser procedure uses heat guided by MRI imaging to target the problem area in your brain. Researchers want to see if this gentler approach can reduce seizures just as effectively while causing less damage to healthy brain tissue.
Many people with temporal lobe epilepsy continue to have seizures even when taking multiple medications. While traditional surgery can help, it requires opening the skull and removing brain tissue, which carries risks. This trial exists to find out whether the new laser treatment can offer similar seizure relief with fewer side effects and a faster recovery.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will be randomly assigned to receive either the new laser surgery or traditional open surgery. Both procedures aim to reduce your seizures by treating the problem area in your temporal lobe. You will have imaging scans, pre-surgery evaluations, the surgical procedure itself, and follow-up visits to monitor your seizure frequency and recovery over time. The study team will track how well each approach works and compare how you feel and function after each type of surgery.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
China
Sponsor
Beijing Tiantan Hospital
Enrollment target
~120 participants
Started
July 2025
Primary completion
January 2027
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kai Zhang, Dr.
Beijing Tiantan Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.