Plain-English translation of NCT06725550 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Sickle Cell Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing whether acupuncture—a treatment where very fine needles are inserted into the skin at specific points on your body—can help manage chronic pain from sickle cell disease. You would be randomly assigned to receive either traditional needle acupuncture or laser acupuncture (which uses a laser device instead of needles). The researchers want to understand not only whether acupuncture reduces your pain, but also how it works by looking at changes in your brain activity and nervous system.
Many people with sickle cell disease suffer from severe chronic pain and often rely on strong pain medications like opioids. This study exists because researchers believe that acupuncture could be a helpful non-medication option to manage pain, and they want to understand the science behind how it works.
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You would visit the study site about 14 times over 6-8 weeks, plus follow-up visits for 12 months. During this time, you would receive 10-12 acupuncture sessions (either with needles or laser) lasting 30 minutes each, given either twice weekly for 5 weeks or once weekly for 12 weeks. At study visits, you would answer health questions, have your pain response tested with mild stimuli, and undergo brain imaging (MRI, EEG, and other scans) to see how the treatment affects your brain. You would continue taking your regular sickle cell medications during the study.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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