Plain-English translation of NCT06726434 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After a stroke, some people develop severe muscle tightness in the foot and lower leg that makes walking difficult—a condition called spastic equinovarus foot. This trial is testing whether a newer, minimally invasive procedure called percutaneous cryoneurotomy (which uses cold to treat the affected nerve) works as well as traditional open surgical nerve surgery. Both approaches aim to permanently reduce the spasticity and improve your ability to walk and move.
While temporary botulinum toxin injections can help spasticity in the short term, they wear off and require repeated treatments. Traditional open surgery is permanent but involves larger incisions and more recovery time. This trial exists to see if the newer freezing technique offers the best of both worlds: permanent relief with less surgical trauma and faster recovery.
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You will be randomly assigned to receive either the newer cryoneurotomy procedure or traditional open surgical neurotomy. The trial involves a nerve block test beforehand to confirm you are a good candidate. After your assigned procedure, you will have follow-up visits to measure how well your foot function improves, how much your spasticity decreases, and how your walking and daily activities are affected. The trial will track your recovery and compare the results between the two groups to see if the newer approach works just as well as traditional surgery.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
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