Plain-English translation of NCT06729762 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is studying a minimally invasive procedure called ultrasound-guided thermal ablation, which uses heat to treat benign (non-cancerous) thyroid nodules. Instead of surgery to remove the nodule, this treatment aims to shrink or destroy the nodule while keeping your thyroid intact. The study will follow patients for at least 12 months to see how well the treatment works and whether nodules stay smaller over time.
Many people with benign thyroid nodules experience cosmetic concerns or symptoms, or worry their nodule might grow. Traditional treatment is often surgery, but not everyone can have or wants an operation. This trial exists to see whether this gentler heat-based approach can be a safe and effective alternative.
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You would receive the ultrasound-guided thermal ablation procedure, which uses ultrasound imaging to guide heat delivery directly to your thyroid nodule. After the procedure, you would return for follow-up visits over at least 12 months to have ultrasound scans and check-ups to monitor how your nodule responds to treatment. The study involves multiple hospitals, so you would be treated at one of the participating medical centers.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
China
Sponsor
Chinese PLA General Hospital
Enrollment target
~1,500 participants
Started
December 2024
Primary completion
December 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lin Yan, MD
Chinese PLA General Hospital
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