Plain-English translation of NCT06730295 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing a new type of radiation therapy called online adaptive stereotactic radiotherapy for early-stage lung cancer that is located in the center of the lung. The treatment adjusts in real time during each session using special imaging, which allows doctors to remove safety margins they normally add around the tumor. The goal is to deliver effective radiation while potentially reducing side effects.
Standard radiation therapy adds extra space around tumors to account for patient movement and positioning changes. This trial is testing whether real-time imaging and adjustment during treatment can be so precise that these safety margins are no longer needed, potentially making treatment safer and more effective.
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You will receive radiation therapy in 3 doses given once daily, with a total dose of 39–42 Gray delivered over a short period. Before each treatment session, the doctors will take two types of imaging scans—a standard CT scan and a 4D breathing scan—to see exactly where your tumor is positioned. The radiation beam will then be adjusted based on these images to match your tumor's location precisely before treatment begins.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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