Recruiting

Using heart imaging to predict dangerous heart rhythms in cardiomyopathy

Plain-English translation of NCT06730464 on ClinicalTrials.gov ↗ · Source last updated December 2024 · Translation generated August 2026 · How we translate trials

What is this trial?

Researchers are studying how heart imaging—specifically MRI scans that show scarring in the heart—can help predict which patients with non-ischemic cardiomyopathy (a weakening of the heart muscle not caused by blocked arteries) are at risk for dangerous, fast heart rhythms. By analyzing patterns of scarring and heart function in 500 patients, the study aims to create a better way to identify who needs preventive devices like an implantable defibrillator.

Patients with cardiomyopathy face an unpredictable risk of life-threatening heart rhythm problems, and doctors currently lack reliable tools to identify which patients are in highest danger. This study hopes to use advanced imaging to spot warning signs earlier and help doctors make better decisions about which patients need protective treatment.

Do you qualify?

You likely qualify if…

you are at least 18 years old
you have been diagnosed with non-ischemic heart disease (dilated cardiomyopathy, non-dilated cardiomyopathy, or heart muscle damage after myocarditis)
you have already had or are scheduled to have a cardiac MRI scan as part of your regular care
you have not had any dangerous heart rhythm events at the time of your first MRI
you are expected to live at least one more year and are in generally good health

You likely don't qualify if…

you are pregnant
you have a life expectancy of less than one year or are in very poor health (unable to do any daily activities)
you have had other types of heart disease (such as ischemic heart disease, congenital heart disease, or right-sided arrhythmogenic cardiomyopathy)
you have previously had documented dangerous heart rhythm events at your first MRI scan
you cannot access the study visits or give written consent

What participation looks like

You will be enrolled if you have already had or are scheduled to have a heart MRI scan as part of your routine medical care. Researchers will collect data from your imaging scans and medical records over time to track which patients develop dangerous heart rhythms and how scar patterns in your heart change. Some participants may be followed for several years as part of this research, but no special medication or invasive procedures are required—the study uses information from imaging and clinical care you are already receiving.

AI-generated summary from trial data · Aug 31, 2026 · Not medical advice

Trial locations(4 sites)

Italy

Humanitas Research Hospital (Rozzano - Milan, Italy), Milan, Italy

Portugal

Hospital de la Luz, Lispon, Portugal

Spain

Teknon Medical Center, Barcelona, Barcelona

Virgen del Rocio University Hospital, Seville, Sevilla

View full record on ClinicalTrials.gov