Plain-English translation of NCT06732284 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is trying to understand why some people with depression experience severe morning grogginess—a condition where you feel groggy, sluggish, and mentally foggy after waking up. Researchers want to see if morning grogginess happens more often in people with depression, and if it affects how quickly they can think clearly and react when they first wake up. The study will compare three groups of people to find out what's different about their brains and sleep patterns.
Morning grogginess can make it harder for people with depression to start their day, go to work or school, or take care of themselves. Doctors don't fully understand why some depressed patients struggle with this more than others, so this research could help create better treatments tailored to each person's needs.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be invited to the Sleep Disorders Unit at the hospital for an overnight sleep study where sensors will monitor your sleep. During this visit, you'll also complete a simple computer-based test the morning after your sleep study—called the Psychomotor Vigilance Task—which measures how quickly and accurately you can react when you first wake up. The whole process involves one night of sleep monitoring and some brief morning testing; no experimental medications are being given in this study.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
France
Sponsor
Centre Hospitalier Universitaire de Nīmes
Enrollment target
~110 participants
Started
November 2025
Primary completion
March 2027
Age range
18 Years – 54 Years
Last updated on clinicaltrials.gov in December 2025.
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Central contact
Elisa EVANGELISTA
CHU de Nimes
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.