Plain-English translation of NCT06732349 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to develop a new urine test that can better predict how quickly your kidney disease might get worse. Your kidneys have two main parts: filters and tiny tubes called tubules. Current kidney disease diagnosis only looks at filter function, but new kidney-protective treatments target the tubules. This study will test whether measuring special substances in your urine—things called urine supersaturation and extracellular vesicles—can give doctors better warning signs of progression.
Kidney disease affects over 800 million people worldwide and is now a leading cause of death. Doctors need better ways to predict which patients will get sicker fastest, so they can start protective treatments earlier. Right now, the available tests don't look at tubular injury, which is what actually drives kidney disease to get worse.
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Your participation is straightforward and adds no burden to your regular care. Urine samples are already collected as part of your routine kidney disease monitoring at the clinic. Researchers will simply use a portion of your sample to measure the new urine markers alongside your standard tests. That's it—no extra visits, procedures, or inconvenience. The study will track how your kidney function changes over time to see if these new markers are better at predicting progression than current methods.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
Netherlands
Sponsor
Erasmus Medical Center
Enrollment target
~556 participants
Started
January 2025
Primary completion
December 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
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Central contact
Sebastian Beckmann, MD
Erasmus Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.