Plain-English translation of NCT06732856 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing whether a new medication called , when combined with standard chemotherapy drugs, can help treat advanced stomach cancer more effectively. Patients receive this combination treatment before surgery to remove the cancer, with the goal of reducing the chance the cancer returns after surgery. The study wants to see if this approach works better than surgery and chemotherapy alone.
Even with current treatments, about one-third of patients with advanced stomach cancer experience cancer recurrence after surgery. Researchers believe giving the new medication combined with chemotherapy before surgery—rather than after—might prevent the cancer from coming back more effectively.
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You would receive the new medication plus three chemotherapy drugs (, , and ) before surgery—this is called neoadjuvant treatment. After completing this chemotherapy regimen, you would have surgery to remove the tumor. The trial involves multiple clinic visits for infusions, blood tests, and imaging scans to monitor how well the treatment is working and track any side effects. The entire process from start of treatment through surgery typically takes several months.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
South Korea