Plain-English translation of NCT06733025 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether surgery for arm muscle stiffness works as well as or better than botulinum toxin injections. Botulinum toxin is a medication already used to treat muscle tightness, and researchers want to see how it compares to surgical treatment. The goal is to help people with arm stiffness regain better function and movement after a stroke, brain injury, or spinal cord injury.
Muscle stiffness in the arm is a common and disabling side effect after brain or spinal cord injury, making it hard to move the arm and use the hand. Right now, injections are the most popular treatment, but surgery may offer longer-lasting results — yet there are very few studies comparing the two approaches.
You likely qualify if…
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If you join this trial, you will first receive a botulinum toxin injection for your arm stiffness. After at least three months, you will then have surgery to correct the muscle tightness. Throughout the study, you will work with a physical or occupational therapist to help with your recovery and improvement in arm function. The study will track how well each treatment works and compare the results.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
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