Plain-English translation of NCT06733376 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing how well different evidence-based talk therapies work for people with PTSD whose symptoms didn't improve after an initial 10-session treatment called Cognitive Processing Therapy. The study aims to find the best second treatment option—whether that's more of the same therapy, a different approach called Prolonged Exposure, or another method called STAIR—to help people who didn't respond the first time.
Many people with PTSD don't get better after their first treatment, but doctors don't yet have clear guidance on what to try next. This study will help identify which patients are likely to need a different approach and what that second treatment should be, so care can be more personalized and effective.
You likely qualify if…
You likely don't qualify if…
You would start by attending 10 therapy sessions of Cognitive Processing Therapy over the course of 2 weeks (about one session per day). One week after finishing, you'll be assessed to see how much your PTSD symptoms have improved. If your symptoms are still moderate to severe, you'll be offered a second round of therapy—either more sessions of the same treatment, Prolonged Exposure, or STAIR therapy—another 10 sessions over 2 weeks. Throughout the study, you'll also complete questionnaires and meet with clinicians for assessments to track your progress.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
United States