Plain-English translation of NCT06733753 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial evaluates ultrasound-guided thermal ablation—a procedure that uses heat to shrink thyroid nodules—for patients with uncertain biopsy results (Bethesda category III or IV). Researchers want to understand how well this treatment works over time and what outcomes patients can expect, especially for those who prefer not to have surgery or are not eligible for it.
Many people have thyroid nodules with biopsy results that are unclear—not clearly benign, but not clearly cancer either. Surgery is one option, but not everyone wants or can have it. This trial exists to see whether this heat treatment is a safe and effective alternative that can help avoid unnecessary surgery.
You likely qualify if…
You likely don't qualify if…
You will receive the ultrasound-guided heat treatment procedure, which uses imaging to guide precise heating of your thyroid nodule. After treatment, you will return for follow-up visits and imaging for at least 12 months to monitor how well the nodule has shrunk and how you are doing. The study involves multiple centers in China and aims to enroll 600 participants total.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
China
Sponsor
Chinese PLA General Hospital
Enrollment target
~600 participants
Started
December 2024
Primary completion
December 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lin Yan
Chinese PLA General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.