Plain-English translation of NCT06738173 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →Researchers are developing a new screening tool based on the bacteria naturally found in your gut. Scientists have discovered that certain bacterial patterns may signal the presence of colorectal cancer or precancerous growths. This study will collect stool samples and medical information from over 1,200 people to see if analyzing these bacterial signatures can improve how doctors screen for colorectal cancer.
Current screening methods like the FIT test sometimes miss cancers or cause unnecessary follow-up procedures. Doctors need better tools to accurately identify who has colorectal cancer or dangerous polyps, and research suggests that gut bacteria patterns might provide that answer.
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You will provide a stool sample and basic health information as part of your regular colorectal cancer screening. Your sample will be analyzed to identify bacterial patterns, and your results will be compared with the findings from your colonoscopy. The study includes a main group of participants and a validation group to confirm that the bacterial test works reliably.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Italy
Enrollment target
~1,202 participants
Started
February 2025
Primary completion
September 2029
Age range
50 Years – 74 Years
Last updated on clinicaltrials.gov in May 2025.
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Central contact
Gianluca Ianiro, MD, PhD
Catholic University of the Sacred Heart
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.