Plain-English translation of NCT06740747 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing intermittent theta-burst stimulation (iTBS), a non-invasive brain stimulation technique, to see if it can reduce negative symptoms of schizophrenia—like reduced emotional expression, motivation, and social engagement—and improve thinking and memory. Researchers will stimulate two specific brain regions over 10 sessions and measure whether this treatment helps compared to a sham (fake) stimulation.
Current treatments for schizophrenia often help with hallucinations and delusions, but negative symptoms and cognitive problems remain difficult to treat. This study explores whether this non-invasive brain stimulation approach might address these harder-to-treat aspects of the condition.
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You would receive 10 brain stimulation sessions over two weeks. Before, immediately after, and four weeks after the treatment, you would have detailed assessments including cognitive tests, brain imaging scans, eye movement tracking, and blood and saliva samples. You would be randomly assigned to either active stimulation or sham stimulation, and neither you nor the researchers would know which group you're in during the study.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
Germany