Plain-English translation of NCT06742697 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a comprehensive exercise and training program called FRAME (Flexibility, Resistance, Aerobic, Movement Execution) for adults with hereditary spastic paraplegia, a condition that causes progressive weakness and stiffness in the legs and makes walking difficult. The program combines stretching, strength training, balance work, and aerobic exercise, customized to each person's needs. Researchers want to see if this approach can help people walk faster and farther.
Hereditary spastic paraplegia causes progressive walking problems, but there hasn't been a comprehensive, well-structured exercise program designed specifically to help these patients improve their walking ability. This trial aims to fill that gap by testing whether a combined approach addressing flexibility, strength, balance, and endurance can make a real difference.
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If you join this trial, you will participate in a personalized exercise program that combines flexibility training, strength exercises, balance work, and aerobic conditioning. The program will be tailored to your specific needs and abilities. You'll attend at least 10 treatment sessions (the exact number and schedule will be customized for you), and researchers will measure your walking speed, endurance, strength, and balance at different points using standard tests like timed walking and sit-to-stand exercises.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Italy