Plain-English translation of NCT06743711 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is checking whether doctors can reliably measure fitness levels in people with severe mental illness — specifically schizophrenia or bipolar disorder. Right now, fitness is rarely measured in people with these conditions, even though they face higher risks of heart disease and early death. The researchers want to understand if simple fitness tests could help doctors better understand and treat their patients.
People with severe mental illness die 15–20 years earlier than others, often from heart disease. But doctors rarely check their fitness levels, even though fitness is a strong sign of heart health and survival in the general population. This study could help change that by showing that fitness testing works well in this group and matters for their care.
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You'll attend one 3-hour visit where you'll have your heart health, body composition, and fitness tested through several exercises — including riding a stationary bike and a more intense cardiopulmonary exercise test. You'll also answer questions about your mental health, substance use, physical activity, sleep, and quality of life. After the visit, you'll wear a small activity sensor for two weeks to track your movement, then answer final questionnaires to complete the study.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Denmark
Sponsor
Bjorn H. Ebdrup
Collaborators
Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital, VentriJect ApS
Enrollment target
~75 participants
Started
January 2025
Primary completion
June 2026
Age range
18 Years – 45 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Bjørn H Ebdrup, Professor and psychiatrist
Mental Health Center Glostrup, Center for Neuropsychiatric Schizophrenia Research
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.