Plain-English translation of NCT06748911 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a new tool called the Navicam capsule—a small, swallowable capsule attached to a string—to help doctors detect Barrett's esophagus more easily. Barrett's esophagus is a condition where stomach acid repeatedly damages the lining of your esophagus, and it can sometimes increase cancer risk. The study wants to see if this capsule device provides a better, less invasive way to screen for and monitor this condition compared to traditional methods.
Current methods for diagnosing Barrett's esophagus require uncomfortable procedures. This trial exists to see if this new capsule device can detect Barrett's esophagus just as well but more comfortably, giving patients and doctors a gentler screening option.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will swallow the Navicam capsule, which is about the size of a large vitamin and attached to a thin string that your doctor controls from outside your body. The capsule takes images as it moves through your esophagus, giving your doctor clear views to look for signs of Barrett's esophagus. The procedure is less invasive than traditional endoscopy, and the capsule is retrieved by gently pulling the string.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Enrollment target
~57 participants
Started
February 2025
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
22 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stephanie McNew
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.